Payesh
2010; 9: 165-172
Accepted: 4 May 2007
[EPub a head of print-25 May 2010]

Objective(s): To determine which factors affects quality of life of patients with chronic liver disease.
Methods: In this cross-sectional study, HRQL of patient with chronic liver disease was measured with SF-36 and demographic questions (age, sex, marital status, educational level) and severity and duration of chronic hepatitis were added to questionnaire.140 patients HRQL scores were compared with the 100 published norms. We used SPSS15and data were analyzed by Independent sample T test &One Way ANOVA & Pearson correlation with P value less than 0.05.
Results: In general HRQL in patient with chronic liver disease was lower than normal population (physical function:48.56 29.01, physical problem:21 30.69 ,bodily pain:41.58 26.17, general health 51.40 20.17, vitality 50.98 25.91,emotional problem:37.56 3.40, social functioning 50.23 30.20, mental health 60.76 24.03)there was meaningful linear correlation between age, education level ,sex, marital status and quality of life.
Conclusion: We conclude that chronic liver disease substantially reduces quality of life patient's especially in physical component but severity and duration of disease had not association with quality of life. Older age, male, lower level of education, singles have poorer quality of life. Regard to the goal of treatment of chronic disease is increscent of life span and improve of their abilities for having better quality of life. In this study we measured quality of life in patients with chronic liver disease maybe this result can change quality of life in this patient.