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Obejective (s): infertile couples receiving IVF / ICSI treatment may be at higher risk of developing psychological or health-related problems. Identification of these groups at risk may enable better allocation for appropriate counseling.
Methods: a total of 1028 (516 women and 512 men) were invited to complete health survey short form (SF-36) questionnaire prior to initiating IVF / ICSI treatment in Vali.e.Asr hospital and Rooyan infertility center.
The patient’s demographic and clinical characteristics were also recorded.
Results: male SF-36 scores were higher than those reported by women. Quality of life increased with advancing age, level of education, economic status, in working women and infertality due to male factor.
Conclusion: Infertile couples are at risk of a sub- optimal quality of life. Psychological counselling, especially support psychotherapy, must be regarded for patients in order to increase their quality of life.

Keywords: Health-related quality of life, Infertility, IVF, ICSI, Iranian SF-36

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