Objective(s): This study aimed to translation and determine the reliability and validity of the Health-related quality of life for women with polycystic ovary syndrome and was done on 190 women with polycystic ovary syndrome referred to selected infertility centers of Tehran during 2010-2011.
Methods: For Translation English version of PCOSQ, Forward-Backward method and to determine the reliability of the instrument, internal consistency was used. For assessing the validity of this questionnaire, Item-Scale correlation and Known groups' comparison were identified. The results were analyzed with SPSS-14.
Results: The results of this study showed that Cronbach's alpha coefficient for all dimensions except menstrual problems were higher than o.7. Also, all questions showed an adequate correlation with their dimensions (r>0.4) and all domains scores except menstrual problems, regarding to BMI showed significant statistical differences (P<0.05).
Conclusion: However, it seems that Iranian version of this questionnaire is an acceptable questionnaire with adequate reliability and validity in all dimensions except for menstrual problems. For obtain better results, further studies with larger sample size and different settings are recommended.

Keywords: Quality of life, Polycystic Ovarian Syndrome, PCOSQ, HR-QoL

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